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Wednesday, April 22, 2020 | History

3 edition of Cancer Chemotherapeutic Agents found in the catalog.

Cancer Chemotherapeutic Agents

Handbook of Clinical Data

by M.R. Sather

  • 255 Want to read
  • 30 Currently reading

Published by Springer .
Written in English

  • Medical,
  • Oncology,
  • Cancer,
  • Chemotherapy,
  • Medical / Oncology,
  • Medical / Nursing

  • The Physical Object
    Number of Pages176
    ID Numbers
    Open LibraryOL12800666M
    ISBN 109024721709
    ISBN 109789024721702

      This book dealing with the methods of evaluation of chemotherapeutic agents is the second in a series of symposia of the Section of Microbiology of the New York Academy of Medicine. Ably organized and edited by Dr. MacLeod contributions are made by leaders in the field of antimicrobial therapy. Chemotherapeutic Effect of Withaferin A in Human Oral Cancer Cells In-Hyoung Yang, Lee-Han Kim, Ji-Ae Shin, Sung-Dae Cho DOI: /jct 2, . Because chemotherapeutic agents target cancer cells in different ways, it’s common for several of these agents to be given together. This strategy increases the potent killing effect of these drugs while reducing the risk that some cells will develop resistance to the drugs. Since chemotherapeutic drugs cannot distinguish between normal cells and cancer cells, both types of cells are affected by chemotherapy. Toxicity of chemotherapeutic agents to normal cells is the cause of unpleasant side effects. However, the value of chemotherapy lies in the fact that the killing effect of chemotherapeutic agents has a.

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Cancer Chemotherapeutic Agents by M.R. Sather Download PDF EPUB FB2

Cancer Chemotherapy: Medical Outline Series discusses the benefits and risks of cancer chemotherapy. This book is composed of 11 chapters that cover the pharmacologic and therapeutic potentials of some chemotherapeutic agents.

The opening chapter briefly considers the pharmacology of cancer chemotherapy. Find many great new & used options and get the best deals for Cancer Chemotherapeutic Agents: Handbook of Clinical Data by M. Sather (, Paperback) at the best online prices at eBay. Free shipping for many products. Here's a comprehensive, yet compact and practical guide to the care and chemotherapeutic treatment of cancer patients.

It encompasses all major chemotherapeutic agents and combinations, investigational and newly approved drugs, and describes their mechanisms of action, indications, metabolism, dose, administration, toxicity, and drug interactions and Cited by: ISBN: OCLC Number: Description: xx, pages: illustrations ; Cancer Chemotherapeutic Agents book cm.

Contents: Prediction of biochemical mechanism of action from the vitro antitumor screen of the National Cancer Institute / Kenneth D. Paull --Antimetabolites --Agents that react with DNA --Topoisomerase II inhibitors --Inhibitors of DNA.

Cancer Chemotherapeutic Agents (ACS Professional Reference Book): Medicine Cancer Chemotherapeutic Agents book Health Science Books @ ce: $ Chemotherapeutic agents inhibit the reproduction of cancer cells by interfering with DNA synthesis and mitosis, causing the cells to stop growing (cytostatic agents) or to die (cytotoxic agents).

Cancer cells that are synthesizing DNA and rapidly dividing are more vulnerable to the effects of many drugs than are those in a resting (non-cycling File Size: 6MB.

Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents) as part of a standardized chemotherapy herapy may be given with a curative intent (which almost always involves combinations of drugs), or it may aim to prolong life or to reduce Other names: chemo.

Specifically, our goals are to (1) highlight novel principles of immune suppression in cancer, which represent the major salient breakthroughs in the field of cancer immunology the last decade, and to (2) discuss the latest thinking in how immunotherapeutic and chemotherapeutic agents might be combined, not Cancer Chemotherapeutic Agents book to defeat mechanisms of tumoral.

The Chemotherapy Source Book, Fourth Edition pulls together all the current information on the chemotherapeutic management of cancer patients, including choice of chemotherapeutic agents, use of combinations, and toxicity of individual drugs.

Organized by disease site, the book brings together pharmacologic and patient management information in one source that clinicians can.

Combination Chemotherapy in the Clinic. There is ample clinical precedent for using multiple agents. An example is the treatment of ALL in children, where 8 active agents have been identified. There is a direct correlation between the number of. The NCI Dictionary of Cancer Terms features 8, terms related to cancer and medicine.

We offer a widget that you can add to your website to let users look up cancer-related terms. Get NCI’s Dictionary of Cancer Terms Widget. Oral complications of cancer chemotherapy result from the chemotherapeutic agent acting on the oral mucosa (ie, direct or primary stomatotoxicity), the patient's inability to contain local, minor oral disease during myelosuppression (ie, indirect or secondary stomatotoxicity), or some combination of Cited by: Etopophos Chemo Management of refractory testicular tumors, in combination with other approved chemotherapeutic agents; Management of small cell lung cancer, first-line, in combination with other approved chemotherapeutic agents; Management of refractory testicular tumors and small cell lung cancer.

exemestane Aromasin Hormone (aromatase inhibitor)File Size: KB. Traditional chemotherapeutic agents are cytotoxic by means of interfering with cell division (mitosis) but cancer cells vary widely in their susceptibility to these agents.

To a large extent, chemotherapy can be thought of as a way to damage or stress cells, which may then lead to cell death if apoptosis is initiated. The Red Book estimates the average wholesale price for chemotherapy agents and is widely utilized by pharmacists.

Table 2 indicates the wholesale cost of some chemotherapy agents published in the Red Book in As can be seen from this analysis, newer oral chemotherapy may be more expensive than the older intravenous by: Chemotherapeutic agents have toxicities that extend beyond their therapeutic effect on malignant cells, and the kidneys are involved in the metabolism of these agents.

Kidney toxicity delay the elimination of anticancer drugs from the body and increase the risk of systemic toxicity. Conventional chemotherapeutics generally cause direct renal tubular injury and electrolyte. Medical Book The Cancer Chemotherapy Handbook It encompasses all major chemotherapeutic agents and combinations, investigational and newly approved drugs, and describes their mechanisms of action, indications, metabolism, dose, administration, toxicity, and drug interactions and incompatibilities.

Abstract. Effective chemotherapeutic agents are limited in their clinical use by the effects they produce on normal cells. The ratio of the doses at which therapeutic effect and toxicity occur is referred to as the therapeutic y, one would like to have at his disposal drugs that have a higher therapeutic index, i.e., maximum therapeutic benefit with virtually no by: 8.

COVID Resources. Reliable information about the coronavirus (COVID) is available from the World Health Organization (current situation, international travel).Numerous and frequently-updated resource results are available from this ’s WebJunction has pulled together information and resources to assist library staff as they consider how to handle.

Book Notes | 1 December Cancer Chemotherapeutic Agents. Handbook of Clinical Data. General principles, summaries of types of agents, summaries of established and new agents, complications of cancer and treatment, tables pertinent to dosage adjustments. Spiralbound as large-pocket handboook.

The Seventh Edition of this pocket reference is a practical, disease-focused guide to the best current medical practice in cancer chemotherapy. In easy-to-follow outline format, the book provides complete coverage of the principles of rational chemotherapy, the chemotherapeutic and biotherapeutic agents available, the treatment of specific cancers, and selected aspects of Reviews: 1.

Colorectal cancer (CRC) is one of the most common cancers in the world. Around 90% of CRC deaths are caused by metastasis, and systemic chemotherapy is the last hope for patients with unresectable metastases of CRC.

Although recent systemic chemotherapy advances have prolonged survival in patients with unresectable CRC, the effectiveness, cost, and side effects Author: Soichiro Murata. This is a list of chemotherapeutic agents, also known as cytotoxic agents, that are known to be of use in chemotherapy for list is organized by type of agent, although the subsections are not necessarily definitive and are subject to revision.

Each drug is listed once (at present), though it might fall in more than one subsection. The first edition of Cancer Chemotherapy, published by Edward S Greenwald inraised the legitimate question of whether patients with cancer benefited from chemotherapy.

Medical oncology, the discipline that specialises in the use of systemic forms of treatment for the management of patients with cancer, had yet to be established. Chemotherapeutic agents Author: Max J Coppes. When cancer chemotherapeutic agents are administered in overdose (orally or by injection) or in the wrong site (intrathecally instead of intravenously), predictable (bone marrow suppression) and.

Chapter 1 gives a brief overview of the key principles of cancer chemotherapy and reviews the clinical settings where chemotherapy is used. Chapter 2 reviews individual chemotherapeutic and biologic agents that are in current clinical use; these agents are presented in alphabetical order according to their generic name.

Nature continues to produce a great wealth of natural molecules endowed with cytotoxic activity toward a large panel of tumor cells. Some of these molecules are used in chemotherapy, and others have shown great anti-tumor and anti-metastatic potential in preclinical trials. This review discusses some examples of these molecules that have been studied in our laboratory and Author: Abdelmajid Zyad, Inass Leouifoudi, Mounir Tilaoui, Hassan AitMouse, Mouna Khouchani, Abdeslam Jaafar.

About this book. The best and most concise single source for state-of-the-art diagnosis and treatment of lung cancer –newly Discusses combined modality therapy and new chemotherapeutic agents which are yielding higher response rates and improved survival when used in the adjuvant setting or concurrent with highly sophisticated radiation.

Title: Hsp90 Inhibitor Geldanamycin and Its Derivatives as Novel Cancer Chemotherapeutic Agents VOLUME: 11 ISSUE: 9 Author(s):Y.

Miyata Affiliation:Department of Cell and Developmental Biology, Graduate School of Biostudies, Kyoto irakawa Oiwake-cho, Sakyo-ku, KyotoJapan. Keywords:hsp90, molecular chaperone, Cited by: Cancer Chemotherapy and Pharmacology addresses a wide range of pharmacologic and oncologic concerns on both experimental and clinical levels.

The primary focus of this rapid publication medium is on new anticancer agents, their experimental screening, preclinical toxicology and pharmacology, single and combined drug administration modalities, and clinical.

[ads2] [toggle title=”Description” state=”open”] Cardiotoxicity is a well-established complication of antineoplastic agents. Cardiomyopathy resulting from anthracyclines is a classic example. In the past decade, an explosion of novel cancer therapies, often targeted and more specific than conventional therapies, has revolutionized oncology therapy and dramatically changed cancer.

Chemotherapy, radiotherapy, and surgery are the most common modalities used to treat a patient with cancer. Many established chemotherapy drugs are anti-proliferative agents, targeting rapidly dividing cancer cells but also damaging non-malignant dividing cells, leading to Cited by:   Lung cancer is a major cause of cancer-related deaths in men and women.

However, since the first edition of Lung Cancer was published 14 years ago, rapid progress in the biology, prevention, diagnosis, and treatment of the disease has been made.

Dipyridamole can modulate the activity of a number of chemotherapeutic agents and may have the ability to enhance their therapeutic index.

We review here the cellular and biochemical mechanisms by which dipyridamole alters cancer cell sensitivity and Cited by: 8. The Chemotherapeutic agents named as follows. S ince antibiotic from synthetic origin is a Che mical Compound so the therapy should be known as CHEMOTHERAPY.

Novel Chemotherapeutic Agents: Preactivation in the Treatment of Cancer and AIDS. Authors: Gulliya, Kirpal S. Free Preview. Because most chemotherapeutic agents are excreted in the urine and feces, it is best to flush the toilet two or three times.

DIF: Cognitive Level: Application REF: p. OBJ: 7. TOP: Nursing Process Step: Evaluation. MSC: NCLEX Client Needs Category: Physiological Integrity.

The nurse is caring for a patient diagnosed with breast cancer. The recent understanding of the molecular mechanisms and targets implicated for cancer chemo-resistance have paved the way to develop a large battery of small molecules (sensitizing agents) that can target resistant factors and reduce the threshold of resistance and allowing their combination with chemotherapeutic drugs to be effective and to.

Tumors do not typically have faster generation times, but instead have many more cells in the active phases of replication and have dysfunctional apoptosis, hence proliferation.

In contrast, normal tissues have a much larger number of cells in the G 0 phase. As a result, cancer cells proceeding through the cell cycle may be more sensitive to chemotherapeutic agents, whereas. PPT 1: Introduction to cancer chemotherapy.

Download PPT file: Cancer Chemotherapy 1. Etiopathology. Apoptosis. Characteristics of cancer cells. The Goal of cancer treatments.

Major approaches to therapy of cancers. Cell cycle and cancer chemotherapy. Cell cycle specific and cell cycle non-specific agents. Log kill hypothesis. Cancer Pharmacology and Pharmacotherapy Reviewis the first book devoted entirely to providing the "must-know" facts on each cancer agent, including their pharmacokinetics, FDA-approved indications,toxicity, interactions, and other important information that is commonly found on board examinations and essential for any clinician or practitioner to : $Novel Chemotherapeutic Agents: Preactivation in the Treatment of Cancer and AIDS.

by Kirpal S. Gulliya. Medical Intelligence Unit. Share your thoughts Complete your review. Tell readers what you thought by rating and reviewing this book. Rate it * You Rated it *Brand: Springer Berlin Heidelberg.In: MacLeod, C.M., Ed., Evaluation of Chemotherapeutic Agents, Columbia University Press, New York, has been cited by the following article: TITLE: Validation of the Trail Making Test B for the Cognitive Assessment of Patients with Cancer in Palliative Care.